CONSUMPTION OF Hibiscus sabdariffa DRIED CALYX ETHANOL EXTRACT IMPROVED REDOX IMBALANCE AND GLUCOSE PLASMA IN VITAMIN B12 RESTRICTION DIET IN RATS

This study aimed to evaluate the effect of Hibiscus sabdariffa L. dried calyx ethanolic (HSE) extract on redox imbalance and glucose plasma vitamin B12 restriction Sprague-Dawley rats. The rat was fed a Vitamin Restriction Diet for 16 weeks treated with HSE as treatment group. One group diet not positive control group, another chow negative B12, MDA, SOD activity enzyme, levels were evaluated in this study. had significant antioxidant capacity terms reducing production free radical scavenging activity. can repair skewed oxidative damage generated by B12-deficient liver. result fasting levels, showed both significantly different all groups. In rats HSE, decrease week sixteen observed, together reduction hepatic imbalance. Treatment protected hepatocytes from caused deficiency.